combi_run_rcurvep.Rd
It simplifies the steps of run_rcurvep()
by wrapping the create_dataset()
in the function.
combi_run_rcurvep( d, n_samples = NULL, vdata = NULL, mask = 0, keep_sets = c("act_set", "resp_set", "fp_set"), ... )
d | Datasets with concentration-response data. Examples are zfishbeh and zfishdev. |
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n_samples | NULL (default) for not to simulate responses or an integer number to indicate the number of responses per concentration to simulate. |
vdata | NULL (default) for not to simulate responses or a vector of numeric responses in vehicle control wells to use as error. This parameter only works when n_samples is not NULL; an experimental feature. |
mask | Default = 0, for no mask (values in the mask column all 0). Use a vector of integers to mask the responses: 1 to mask the response at the highest concentration; 2 to mask the response at the second highest concentration, and so on. If mask column exists, the setting will be ignored. |
keep_sets | The types of output to be reported. Allowed values: act_set, resp_set, fp_set. Multiple values are allowed. act_set is the must.
|
... | Curvep settings.
See |
An rcurvep object. It has two components: result, config
The result component is also a list of output sets depending on the parameter, keep_sets.
The config component is a curvep_config object.
Often used columns in the act_set: AUC (area under the curve), wAUC (weighted AUC), POD (point-of-departure), EC50 (Half maximal effective concentration), nCorrected (number of corrected points).
data(zfishbeh) # 2 simulated sample curves + # using two thresholds + # mask the response at the higest concentration # only to output the act_set out <- combi_run_rcurvep( zfishbeh, n_samples = 2, TRSH = c(5, 10), mask = 1, keep_sets = "act_set") # create the zfishdev_act dataset # \donttest{ data(zfishdev_all) zfishdev_act <- combi_run_rcurvep( zfishdev_all, n_samples = 100, keep_sets = c("act_set"),TRSH = seq(5, 95, by = 5), RNGE = 1000000, CARR = 20, seed = 300 ) # }